Review Article | Volume 11, Issue 2, March, 2023

Revisiting microbial pectinases: An understanding between structure-functional relationship in the arena of genetic engineering

Surojit Bera Evangeline Rajan Sandali Shakya Imasha Perera Sasini Wijewarna Movinya Semini   

Open Access   

Published:  Jan 22, 2023

DOI: 10.7324/JABB.2023.27206

In the food and beverage sector, biotechnological applications of pectinase have been increasing day by day. However, subdued production volume and low purity of the pectinase in commercial scale still remain a challenge. As a result, researchers are continuously exploring the opportunity to express modern tools such as genetic engineering, metagenomic study, and metabolic engineering to exploit microbes as promising source for pectinases. Although this enzyme can be found naturally in plants, microbial pectinases retained a high value preference due to its easy fermentation in different bioreactors and inimitable physicochemical attributes. Microbial pectinase has immense potential to contribute in different areas such as textile industries, pharma sector, paper, and pulp industry, environmental engineering, agricultural economics in addition to that food, and beverage industries. The assertion of gene manipulation for better production of pectinase by means of elementary molecular devices and conventional fermentation procedures has been correlated in this study to get a bird’s eye view in the structure-functional relationship of the microbial pectinases.

Keyword:     Pectinase Genetic engineering Bioreactors Metagenomic study


Bera S, Rajan E, Shakya S, Perera I, Wijewarna S, Semini M. Revisiting microbial pectinases: An understanding between a structure-functional relationship in the arena of genetic engineering. J App Biol Biotech. 2023;11(02):63-74.

Copyright: Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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