Silver nanoparticles decorated natural products doped polyaniline hybrid materials for biomedical applications

K. Satish K. Sumangala Bhat Y. S. Ravikumar M. N. K. Harish   

Open Access   

Published:  Nov 11, 2022

DOI: 10.7324/JABB.2023.110217

The use of silver nanoparticles (AgNPs) and other combinations of AgNPs with various biomaterials is being exploited by the scientific community to regulate bacterial growth. In the present study, one-pot synthesis of AgNPs functionalized natural products doped polyaniline hybrid materials (SNPs) has been successfully synthesized The signature of the functional groups, morphology, and elemental composition of the new SNPs were studied by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction techniques. The synthesized SNPs were investigated for their antibacterial potency against Escherichia coli, Klebsiella pneumoniae, Streptococcus mutans, and Enterococcus faecalis and antifungal properties against Aspergillus niger, Fusarium oxysporum, Epidermophyton floccosum, and Trichophyton rubrum. Our results have demonstrated the antibacterial activities of new SNPs of gallic acid and myoinositol on S. mutans and E. faecalis with minimal inhibitory concentration and minimal bactericidal concentration values of 1.5 and 2 mg/mL, respectively. The SNP of phloroglucinol was effective against E. floccosum and T. rubrum at 5 mg/mL concentrations. This study indicates that SNPs exhibited significant antibacterial and antifungal activity against selected strains of bacteria and fungi when compared to AgNPs functionalized polyaniline hybrid materials (SPs) alone.

Keyword:     Dopants PANI Nanocomposite Antibacterial Antifungal


Satish K, Bhat KS, Ravikumar YS, Harish MNK. Silver nanoparticles decorated natural products doped polyaniline hybrid materials for biomedical applications. J App Biol Biotech. 2022.

Copyright: Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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