Silver nanoparticles decorated natural products doped polyaniline hybrid materials for biomedical applications

K. Satish K. Sumangala Bhat Y. S. Ravikumar M. N. K. Harish   

Open Access   

Published:  Nov 11, 2022

DOI: 10.7324/JABB.2023.110217
Abstract

The use of silver nanoparticles (AgNPs) and other combinations of AgNPs with various biomaterials is being exploited by the scientific community to regulate bacterial growth. In the present study, one-pot synthesis of AgNPs functionalized natural products doped polyaniline hybrid materials (SNPs) has been successfully synthesized The signature of the functional groups, morphology, and elemental composition of the new SNPs were studied by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction techniques. The synthesized SNPs were investigated for their antibacterial potency against Escherichia coli, Klebsiella pneumoniae, Streptococcus mutans, and Enterococcus faecalis and antifungal properties against Aspergillus niger, Fusarium oxysporum, Epidermophyton floccosum, and Trichophyton rubrum. Our results have demonstrated the antibacterial activities of new SNPs of gallic acid and myoinositol on S. mutans and E. faecalis with minimal inhibitory concentration and minimal bactericidal concentration values of 1.5 and 2 mg/mL, respectively. The SNP of phloroglucinol was effective against E. floccosum and T. rubrum at 5 mg/mL concentrations. This study indicates that SNPs exhibited significant antibacterial and antifungal activity against selected strains of bacteria and fungi when compared to AgNPs functionalized polyaniline hybrid materials (SPs) alone.


Keyword:     Dopants PANI Nanocomposite Antibacterial Antifungal


Citation:

Satish K, Bhat KS, Ravikumar YS, Harish MNK. Silver nanoparticles decorated natural products doped polyaniline hybrid materials for biomedical applications. J App Biol Biotech. 2022. https://doi.org/10.7324/JABB.2023.110217

Copyright: Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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Reference

1. Yetisgin AA, Cetinel S, Zuvin M, Kosar A, Kutlu O. Therapeutic nanoparticles and their targeted delivery applications. Molecules 2020;25:2193.https://doi.org/10.3390/molecules25092193

2. Baig N, Kammakakam I, Falath W. Nanomaterials: A review of synthesis methods, properties, recent progress, and challenges. Mater Adv 2021;2:1821-71.https://doi.org/10.1039/D0MA00807A

3. Zhang D, Ma XL, Gu Y, Huang H, Zhang GW. Green synthesis of metallic nanoparticles and their potential applications to treat cancer. Front Chem 2020;8:1-18.https://doi.org/10.3389/fchem.2020.00799

4. Dada AO, Adekola FA, Dada FE, Adelani-Akande AT, Bello MO, Okonkwo CR, et al. Silver nanoparticle synthesis by Acalypha wilkesiana extract: Phytochemical screening, characterization, influence of operational parameters, and preliminary antibacterial testing. Heliyon 2019;5:e02517.https://doi.org/10.1016/j.heliyon.2019.e02517

5. Delfi M, Ghomi M, Zarrabi A, Mohammadinejad R, Taraghdari ZB, Ashrafizadeh M, et al. Functionalization of polymers and nanomaterials for biomedical applications: Antimicrobial platforms and drug carriers. Prosthesis 2020;2:117-39.https://doi.org/10.3390/prosthesis2020012

6. Ren Q, Ga L, Lu Z, Ai J, Wang T. Aptamer-functionalized nanomaterials for biological applications. Mater Chem Front 2020;4:1569-85.https://doi.org/10.1039/C9QM00779B

7. Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov 2021;20:101-24.https://doi.org/10.1038/s41573-020-0090-8

8. Mathew T, Sree RA, Aishwarya S, Kounaina K, Patil AG, Satapathy P, et al. Graphene-based functional nanomaterials for biomedical and bioanalysis applications. FlatChem. 2020;23:100184.https://doi.org/10.1016/j.flatc.2020.100184

9. Patra JK, Das G, Fraceto LF, Campos EV, Rodriguez-Torres MD, Acosta-Torres LS, et al. Nano based drug delivery systems: Recent developments and future prospects. J Nanobiotechnol 2018;16:1-33.https://doi.org/10.1186/s12951-018-0392-8

10. Atta UR, Iqbal MC. Frontiers in Anti-infective Drug Discovery. Vol. 8. Singapore: Bentham Science Publishers; 2020.

11. Leon-Buitimea A, Garza-Cárdenas CR, Garza-Cervantes JA, Lerma-Escalera JA, Morones-Ramirez JR. The demand for new antibiotics: Antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design. Front Microbiol 2020;11:1669.https://doi.org/10.3389/fmicb.2020.01669

12. Prasad A, Devi AT, Prasad MN, Zameer F, Shruthi G, Shivamallu C. Phyto anti-biofilm elicitors as potential inhibitors of Helicobacter pylori. 3 Biotech 2019;9:1-9.https://doi.org/10.1007/s13205-019-1582-2

13. Younis NS, El Semary NA, Mohamed ME. Silver nanoparticles green synthesis via Cyanobacterium Phormidium sp.: Characterization, wound healing, antioxidant, antibacterial, and anti-inflammatory activities. Eur Rev Med Pharmacol Sci 2021;25:3083-96.

14. Gupta D, Chauhan P. Green synthesis of silver nanoparticles involving extract of plants of different taxonomic groups. J Nanomed Res 2017;5:00110.https://doi.org/10.15406/jnmr.2017.05.00110

15. Vanlalveni C, Lallianrawna S, Biswas A, Selvaraj M, Changmai B, Rokhum SL. Green synthesis of silver nanoparticles using plant extracts and their antimicrobial activities: A review of recent literature. RSC Adv 2021;11:2804-37.https://doi.org/10.1039/D0RA09941D

16. Iftikhar M, Zahoor M, Naz S, Nazir N, Batiha GE, Ullah R, et al. Green synthesis of silver nanoparticles using Grewia optiva leaf aqueous extract and isolated compounds as reducing agent and their biological activities. J Nanomater 2020;2020:8949674.https://doi.org/10.1155/2020/8949674

17. Loo YY, Rukayadi Y, Nor-Khaizura MA, Kuan CH, Chieng BW, Nishibuchi M, et al. In vitro antimicrobial activity of green synthesized silver nanoparticles against selected gram-negative foodborne pathogens. Front Microbiol 2018;9:1555.https://doi.org/10.3389/fmicb.2018.01555

18. Yin IX, Zhang J, Zhao IS, Mei ML, Li Q, Chu CH. The antibacterialmechanism of silver nanoparticles and its application in dentistry. Int J Nanomed 2020;15:2555-62.https://doi.org/10.2147/IJN.S246764

19. Bruna T, Maldonado-Bravo F, Jara P, Caro N. Silver nanoparticles and their antibacterial applications. Int J Mol Sci 2021;22:7202.https://doi.org/10.3390/ijms22137202

20. Mussin JE, Roldan MV, Rojas F, Sosa MD, Pellegri N, Giusiano G. Antifungal activity of silver nanoparticles in combination with ketoconazole against Malassezia furfur. Amb Express 2019;9:1-9.https://doi.org/10.1186/s13568-019-0857-7

21. Patil AG, Kounaina K, Aishwarya S, Harshitha N, Satapathy P, Hudeda SP, et al. Myco-nanotechnology for sustainable agriculture: Challenges and opportunities. In: Yadav AN, editor. Recent Trends in Mycological Research. Cham: Springer; 2021. p. 457-79.https://doi.org/10.1007/978-3-030-60659-6_20

22. Andleeb S, Tariq F, Muneer A, Nazir T, Shahid B, Latif Z, et al. In vitro bactericidal, antidiabetic, cytotoxic, anticoagulant, and hemolytic effect of green-synthesized silver nanoparticles using Allium sativum clove extract incubated at various temperatures. Green Proc Synthesis 2020;9:538-53.https://doi.org/10.1515/gps-2020-0051

23. Karthika V, AlSalhi MS, Devanesan S, Gopinath K, Arumugam A, Govindarajan M. Chitosan overlaid Fe3O4/rGO nanocomposite for targeted drug delivery, imaging, and biomedical applications. Sci Rep 2020;10:1-7.https://doi.org/10.1038/s41598-020-76015-3

24. Femi-Adepoju AG, Adepoju AO, Fatoba PO, Olayemi VT. Biosynthesis, characterization and antimicrobial potency of silver nanoparticles fabricated from Phymatode scolopendria (Burm. F.) Ching. Int J Curr Res 2018;10:76229-33.

25. Li Z, Gong L. Research progress on applications of polyaniline (PANI) for electrochemical energy storage and conversion. Materials 2020;13:548.https://doi.org/10.3390/ma13030548

26. Gaikwad P, Devendrachari MC, Thimmappa R, Paswan B, Raja Kottaichamy A, Kotresh HM, et al. Galvanic cell type sensor for soil moisture analysis. Anal Chem 2015;87:7439-45.https://doi.org/10.1021/acs.analchem.5b01653

27. Sudhakara SM, Devendrachari MC, Kotresh HM, Khan F. Silver nanoparticles decorated phthalocyanine doped polyaniline for the simultaneous electrochemical detection of hydroquinone and catechol. J Electroanal Chem 2021;884:115071.https://doi.org/10.1016/j.jelechem.2021.115071

28. Sudhakara SM, Devendrachari MC, Kotresh HM, Khan F. Phthalocyanine pendented polyaniline via amide linkage for an electrochemical sensing of H2O2. Microchem J 2021;161:105781.https://doi.org/10.1016/j.microc.2020.105781

29. Sudhakara SM, Kotresh HM, Devendrachari MC, Khan F. Synthesis and electrochemical investigation of tetra amino cobalt (II) phthalocyanine functionalized polyaniline nanofiber for the selective detection of dopamine. Electroanalysis 2020;32:1807-17.https://doi.org/10.1002/elan.202000067

30. Zare EN, Makvandi P, Ashtari B, Rossi F, Motahari A, Perale G. Progress in conductive polyaniline-based nanocomposites for biomedical applications: A review. J Med Chem 2019;63:1-22.https://doi.org/10.1021/acs.jmedchem.9b00803

31. Aneja KR. Experiments in Microbiology Plant Pathology and Biotechnology. 4th ed. New Delhi: New Age International Publishers; 2003.

32. McClenny N. Laboratory detection and identification of Aspergillus species by microscopic observation and culture: The traditional approach. Med Mycol Supple 2005;43:S125-8.https://doi.org/10.1080/13693780500052222

33. Butoi B, Groza A, Dinca P, Balan A, Barna V. Morphological and structural analysis of polyaniline and poly (o-anisidine) layers generated in a DC glow discharge plasma by using an oblique angle electrode deposition configuration. Polymers 2017;9:732.https://doi.org/10.3390/polym9120732

34. Mady FM, Shaker MA. Enhanced anticancer activity and oral bioavailability of ellagic acid through encapsulation in biodegradable polymeric nanoparticles. Int J Nanomed 2017;12:7405-17.https://doi.org/10.2147/IJN.S147740

35. Azizian-Shermeh O, Einali A, Ghasemi A. Rapid biologically one-step synthesis of stable bioactive silver nanoparticles using Osage orange (Maclura pomifera) leaf extract and their antimicrobial activities. Adv Powder Technol 2017;28:3164-71.https://doi.org/10.1016/j.apt.2017.10.001

36. Jogaiah S, Kurjogi M, Abdelrahman M, Hanumanthappa N, Tran LS. Ganoderma applanatum-mediated green synthesis of silver nanoparticles: Structural characterization, and in vitro and in vivo biomedical and agrochemical properties. Arabian J Chem 2019;12:1108-20.https://doi.org/10.1016/j.arabjc.2017.12.002

37. Ngemenya MN, Djeukem GG, Nyongbela KD, Bate PN, Babiaka SB, Monya E, et al. Microbial, phytochemical, toxicity analyses and antibacterial activity against multidrug resistant bacteria of some traditional remedies sold in Buea Southwest Cameroon. BMC Complement Alternat Med 2019;19:1-11.https://doi.org/10.1186/s12906-019-2563-z

38. Rahaman A, Choudhary MI, Yousuf S. Science of Spices and Culinary Herbs-latest Laboratory, Pre-clinical, and Clinical Studies. Vol. 2. Singapore: Bentham Science Publishers; 2020.

39. Barbieri R, Coppo E, Marchese A, Daglia M, Sobarzo-Sánchez E, Nabavi SF, et al. Phytochemicals for human disease: An update on plant-derived compounds antibacterial activity. Microbiol Res 2017;196:44-68.https://doi.org/10.1016/j.micres.2016.12.003

40. Gorniak I, Bartoszewski R, Kroliczewski J. Comprehensive review of antimicrobial activities of plant flavonoids. Phytochem Rev 2019;18:241-72.https://doi.org/10.1007/s11101-018-9591-z

41. Satapathy P, Khan K, Devi AT, Patil AG, Govindaraju AM, Gopal S, et al. Synthetic gutomics: Deciphering the microbial code for futuristic diagnosis and personalized medicine. In: Volker G, Andrew SB, Sarvesh S, editors. Methods in Microbiology. United States: Academic Press Inc.; 2019. p. 197-225.https://doi.org/10.1016/bs.mim.2019.02.001

42. Naraginti S, Li Y. Preliminary investigation of catalytic, antioxidant, anticancer and bactericidal activity of green synthesized silver and gold nanoparticles using Actinidia deliciosa. J Photochem Photobiol B Biol 2017;170:225-34.https://doi.org/10.1016/j.jphotobiol.2017.03.023

43. Shaban M, Rabia M, Fathallah W, El-Mawgoud NA, Mahmoud A, Hussien H, et al. Preparation and characterization of polyaniline and Ag/polyaniline composite nanoporous particles and their antimicrobial activities. J Polym Environ 2018;26:434-42.https://doi.org/10.1007/s10924-017-0937-1

44. Roy A, Bulut O, Some S, Mandal AK, Yilmaz MD. Green synthesis of silver nanoparticles: Biomolecule-nanoparticle organizations targeting antimicrobial activity. RSC Adv 2019;9:2673-702.https://doi.org/10.1039/C8RA08982E

45. Kumari M, Giri VP, Pandey S, Kumar M, Katiyar R, Nautiyal CS, et al. An insight into the mechanism of antifungal activity of biogenic nanoparticles than their chemical counterparts. Pestic Biochem Physiol 2019;157:45-52.https://doi.org/10.1016/j.pestbp.2019.03.005

46. Guimaraes A, Venancio A, Abrunhosa L. Antifungal effect of organic acids from lactic acid bacteria on Penicillium nordicum. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2018;35:1803-18.https://doi.org/10.1080/19440049.2018.1500718

47. Kuppusamy P, Yusoff MM, Maniam GP, Govindan N. Biosynthesis of metallic nanoparticles using plant derivatives and their new avenues in pharmacological applications-an updated report. Saudi Pharm J 2016;24:473-84.https://doi.org/10.1016/j.jsps.2014.11.013

48. Xia ZK, Ma QH, Li SY, Zhang DQ, Cong L, Tian YL, et al. The antifungal effect of silver nanoparticles on Trichosporon asahii. J Microbiol Immunol Infect 2016;49:182-8.https://doi.org/10.1016/j.jmii.2014.04.013

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