Published:  Jun 19, 2017DOI: 10.7324/JABB.2017.50314
Meat products can be made healthier by optimizing the concentrations of bioactive compounds present in meat e.g. CLA, L-Carnitine etc. Different strategies for modifying the concentration of healthy compounds in meat to produce safe and healthier functional food products are discussed in the review. These strategies include meat production, handling, storage and utilization processes. The assessment of these functional food products is necessary to measure the functional capacity of these foods. Research in the field of intervention studies on functional variability of modified meat products in humans have also been discussed.
Nisa AU, Zahra N, Hina S, Masood S, Javed A, ManzarInam S. Development of Meat-based Functional Foods; A Review. J App Biol Biotech. 2017; 5 (03): 086-092.
1. Diplock AT. Scientific Concepts of Functional Foods in Europe. Consensus Document British Journal of Nutrition. 1999; 81:1–27.
2. DentaliS. Regulation of functional foods and dietary supplements. Food Technology. 2002;56: 89-94.
3. Hasler CM. Functional foods: their role in disease prevention and health promotion. Food Technology. 1988; 52: 63–70.
4. Heasman M, Mellentin J. The functional foods revolution. London: Earthscan Publications; 2001.
5. Pszczola DE, Katz F, Giese J. Research trends in healthful foods. Food Technology. 2002; 54: 45–52.
6. Schmidl MK, Labuza TP. Essentials of functional foods. Gaitherburg, MD: Aspen Publishers; 2000.
7. Mattila-SandholmT, Saarela M. Functional dairy products. Boca Raton, FL: CRC Press; 2000.
8. Biesalski HK. Meat as a component of a healthy diet – are there any risks or benefits if meat is avoided in the diet?. Meat Science. 2005; 70: 509–524.
9. Chan W. Macronutrients in meat. In: Jensen WK, Devine C, Dikeman M, editors. Encyclopedia of meat sciences, Oxford: Elsevier; 2004, p. 614–618.
10. MulvihillB. 2004. Micronutrients in meat. In: JensenWK, Devine C, Dikeman M,editors. Encyclopedia of meat sciences,Oxford: Elsevier; 2004, p. 618–623.
11. Ovesen L. Cardiovascular and obesity health concerns. In: Jensen WK, Devine C, Dikeman M,editors. Encyclopedia of meat sciences.Oxford: Elsevier; 2004a, p. 623–628.
12. Ovesen L. Cancer health concerns. In: Jensen WK, Devine C, Dikeman M,editors. Encyclopedia of meat sciences. Oxford: Elsevier; 2004b, p. 628–633.
13. Valsta LM, Tapanainen H,Mannisto S. Meat fats in nutrition. Meat Science. 2005; 70: 525–530.
14. Jimenez ColmeneroF, Herrero A, Cofrades S, Ruiz-Capillas C. Meat and functional foods. In: Hui YH,editor. Handbook of meat and meat processing. Boca Raton: CRC Press. Taylor & Francis Group; 2012, p. 225–248.
15. Jimenez-Colmenero F, Sanchez-Muniz FJ, Olmedilla-Alonso B. Design and development of meat-based functional foods with walnut: Technological, nutritional and health impact. Food Chemistry. 2010;123: 959-967.
16. Jimenez-Colmenero F, Carballo J, Cofrades S. Healthier meat and meat products: their role as functional foods. Meat Science.2001; 59: 5-13.
17. Wildman REC. Nutraceuticals: a brief review of historical and teleological aspects. In: Wildman REC, editor. Handbook of nutraceuticals and functional foods.Boca Raton, FL: CRC Press; 2000a,p. 1–12.
18. Wildman REC. 2000b. Classifying nutraceuticals. In: Wildman REC, editor. Handbook of nutraceuticals and functional foods. Boca Raton, FL: CRC Press; 2000b, p. 13–30.
19. Krajcovicova-Kudlackova M, Simoncic R, Bederova A, Babinska K, Beder I. Correlation of carnitine levels to methionine and lysine intake. Physiological Research. 2000;49: 399-402.
20. Mir PS, McAllister TA, Scott S, Aalhus J, Baron V, McCartney D, Weselake RJ. Conjugated linoleic acid–enriched beef production. The American journal of Clinical Nutrition. 2004; 79: 1207-1211.
21. Gnadig S, Xue Y, Berdeaux O, Chardigny JM, Sebedio JL, Mattila-Sandholm T, Saarela M. Conjugated linoleic acid (CLA) as a functional ingredient. Functional Dairy Products. 2003; 263-298.
22. Nagao K, Yanagita T. Conjugated fatty acids in food and their health benefits. Journal of Bioscience and Bioengineering. 2005;100: 152-157.
23. Watkins BA, Li Y. Conjugated linoleic acid: the present state of knowledge. Handbook of nutraceuticals and functional foods; 2001, p. 445-476.
24. Dhiman TR, Nam SH, Ure AL. Factors affecting conjugated linoleic acid content in milk and meat. Critical Reviews in Food Science and Nutrition. 2005;45: 463-482.
25. Herzallah SM, Humeid MA, Al-Ismail KM. Effect of heating and processing methods of milk and dairy products on conjugated linoleic acid and trans fatty acid isomer content. Journal of Dairy Science. 2005; 88: 1301-1310.
26. Sieber R, Collomb M, Aeschlimann A, Eyer H, Jelen. Impact of microbial cultures on conjugated linoleic acid in dairy products – a review. International Dairy Journal. 2004; 14: 1–15.
27. Larsson SC, Bergkvist L, Wolk A. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. The American Journal of Clinical Nutrition. 2005;82: 894-900.
28. Azain MJ. Conjugated linoleic acid and its effects on animal products and health in single-stomached animals. Proceedings of the Nutrition Society. 2003; 62: 319-328.
29. Lindsay DG. Maximizing the functional benefits of plants foods. In: Gibson GR, Williams CM,editors. Functional foods. Boca Raton, FL: CRC Press; 2000, p. 183–208.
30. Langseth L. 2000. Antioxidants and their effect on health. In:Schmidl MK, Labuza TP, editors. Essentials of functional foods. Gaithersburg, MD: Aspen Publication; 2000, p. 303–317.
31. Decker EA, Livisay SA, Zhou S. Mechanisms of endogenous skeletal muscle antioxidants: chemical and physical aspects. In: Decker EA, Faustman C, Lopez-Bote CJ, editors. Antioxidants in Muscle Foods: Nutritional Strategies to Improve Quality. John Wiley & Sons, Inc: NY, USA; 2000, p. 25–60.
32. Brown CE. Interactions among carnosine, anserine, ophidine and copper in biochemical adaptation. Journal of Theoretical Biology. 1981;88: 245-256.
33. Hipkiss AR, Brownson C. A possible new role for the anti-ageing peptide carnosine. Cellular and Molecular Life Sciences. 2000;57: 747-753.
34. Hipkiss AR, Preston JE, Himsworth DTM, Worthington VC, Keown M, Michaelis J, Abbott N. Pluripotent Protective Effects of Carnosine, a Naturally Occurring Dipeptidea. Annals of the New York Academy of Sciences. 1998;854: 37-53.
35. Park YJ, Volpe SL, Decker EA. Quantitation of carnosine in human plasma after dietary consumption of beef. Journal of Agricultural and Food Chemistry. 2005;53: 4736-4739.
36. Held U. Carnitine enhanced performance. Ingredients, Health and Nutrition. 2005;8: 12-13.
37. Shimada K, Sakuma Y, Wakamatsu J, Fukushima M, Sekikawa M, Kuchida K,Mikami M. Species and muscle differences in L-carnitine levels in skeletal muscles based on a new simple assay. Meat Science. 2004;68: 357-362.
38. Shimura S, Hasegawa TJ. Changes of lipid concentrations in liver and serum by administration of carnitine added diets in rats. Journal of Veterinary Medical Science. 1993; 55: 845–847.
39. Vescovo G, Ravara B, Gobbo V, Sandri M, Angelini A, Della Barbera M, DallaLibera L. L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure. American Journal of Physiology-Cell Physiology. 2002; 283: 802-810.
40. Arihara K. Strategies for designing novel functional meat products. Meat Science. 2006; 74: 219-229.
41. Arhiara K, Ohata M. Functional meat products. In: Toldra F, editor. Handbook of meat processing. Ames, Iowa: Wiley-Blackwell; 2010, p. 423–439.
42. Fernandezâ€Gines JM, Fernandezâ€Lopez J, Sayasâ€Barbera E, Perezâ€Alvarez J. Meat products as functional foods: A review. Journal of Food Science. 2005; 70: 37-43.
43. Jimenez-Colmenero F, Reig M, Toldra F. 11 New Approaches. Advanced technologies for meat processing; 2006.
44. Jimenez-ColmeneroF. Meat based functional foods. In: Hui YH, editor. Handbook of food products manufacturing. New Jersey: John Wiley & Son, Inc; 2007a, p. 989–1015.
45. Weiss J, Gibis M, Schuh V, Salminen H. Advances in ingredient and processing systems for meat and meat products. Meat Science. 2010; 86: 196-213.
46. Zhang W, Xiao S, Samaraweera H, Lee EJ, Ahn DU. Improving functional value of meat products. Meat Science. 2010;86: 15-31.
47. Raes K, De Smet S, Demeyer D.Effect of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat: a review. Animal Feed Science and Technology. 2004;113: 199-221.
48. Scollan N, Hocquette JF, Nuernberg K, Dannenberger D, Richardson I, Moloney A. Innovations in beef production systems that enhance the nutritional and health value of beef lipids and their relationship with meat quality. Meat Science. 2006; 74: 17-33.
49. Wood JD, Enser M, Richardson RI, Whittington FM. 2008. Fatty acids in meat and meat products. In: Chow CK, editor. Fatty acids in foods and their health implications. Boca Raton: CRC Press, Taylor & Francis Group; 2008, p. 87–107.
50. Lynch PB,Kerry J. UtiIizing Diet to Incorporate Bioactive Compounds and Improve the NutritionaIQuaIity of MuscIe Foods. In: Decker E, Faustman C, Lopez-Bote C, editors.Antioxidants in Muscle Foods: Nutritional Strategies to Improve Quality. John Wiley and Sons: New York, USA; 2000, p. 455-480.
51. Schmid A, Collomb M, Sieber R, Bee G. Conjugated linoleic acid in meat and meat products: A review. Meat Science. 2006;73: 29-41.
52. Clarke AD. Reduction of cholesterol levels in meat, poultry and fish products. In: Pearson AM, Dutson TR, editors.Production and processing of healthy meat, poultry and fish products. London: Blackie Academic & Professional; 1997, p. 101-117.
53. Bass JJ, Butler-Hogg BW, Kirton AH. Practical methods of controlling fatness in farm animals. In:Wood JD, Fisher AV, editors.Reducing fat in meat animals. London, UK: Elsevier Applied Science; 1990, p. 145-200.
54. Hays VW,Preston RL. Nutrition and feeding management to alter carcass composition of pigs and cattle. In: Hafs HD, Zimbelman RG, editors. Low-fat meats:Design strategies and human implications. London: Academic Press; 1994, p. 13-34.
55. Moloney AP. Reducing fats in raw meat. In: Williams C, Buttriss J, editors. Improving the fat content of foods. Boca Raton, FL: CRC Press and Woodhead Publishing Limited; 2006, p. 313-335.
56. Goutefongea R, Dumont JP. 1990. Developments in low-fat meat and meat products. In: Wood JD, Fisher AV, editors. Reducing fat in Meat animals. London: Elsevier Applied Science; 1990, p. 398-436.
57. Solomon MB, Eastridge JS, Paroczay EW. Transgenic Farm Animals. In Meat biotechnology. New York: Springer; 2008
58. Saeki K, Matsumoto K, Kinoshita M, Suzuki I, Tasaka Y, Kano K, Hosoi Y. Functional expression of a Δ12 fatty acid desaturase gene from spinach in transgenic pigs. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101: 6361-6366.
59. Lai LX, Kang JX, Li RF,Wang JD, Witt WT, Yong HY, Hao YH, et al. Generation of cloned transgenic pigs rich in omega-3 fatty acids. Nature biotechnology. 2006;24: 435-436.
60. Jimenez-Colmenero F. Technologies for developing low-fat meat products. Trends in Food Science and Technology. 1996; 7: 41–48.
61. Keeton JT. Low-fat meat products—technological problems with processing. Meat Science. 1994;36: 261-276.
62. Kerry JF, Kerry JP. Producing low-fat meat products. In: Williams C, Buttriss J,editors. Improving the fat content of foods. Cambridge, UK: Woodhead Publishing Limited and CRC Press LLC; 2006, 336–379.
63. Jimenez-Colmenero F. Healthier lipid formulation approaches in meat based functional foods. Technological options for replacement of meat fats by non-meat fats. Trends in Food Science and Technology. 2007b; 18: 567–578.
64. Baublits RT, Pohlman FW, Brown AH, Johnson ZB, Proctor A, Sawyer J, Galloway DL. Injection of conjugated linoleic acid into beef strip loins. Meat Science. 2007; 75: 84-93.
65. Martin D, Ruiz J, Kivikari R, Puolanne E. Partial replacement of pork fat by conjugated linoleic acid and/or olive oil in liver pâtés: Effect on physicochemical characteristics and oxidative stability. Meat Science. 2008; 80: 496-504.
66. Juarez M, Marco A, Brunton N, Lynch B, Troy DJ, Mullen AM. Cooking effect on fatty acid profile of pork breakfast sausages enriched in conjugated linoleic acid by dietary supplementation or direct addition. Food Chemistry. 2009;117: 393-397.
67. Madden UA, Osweiler GD,Knipe L, Beran GW, Beitz DC.Effects of Eubacteriumcoprostanoligenes and Lactobacillus on pH, lipid content, and cholesterol of fermented pork and mutton sausageâ€type mixes. Journal of Food Science. 1999;64: 903-908.
68. Ammor MS, Mayo B. Selection criteria for lactic acid bacteria to be used as functional starter cultures in dry sausage production: An update. Meat Science. 2007;76: 138-146.
69. De Vuyst L, Falony G, Leroy F. Probiotics in fermented sausages. Meat Science. 2008;80: 75-78.
70. Khan MI, Arshad MS, Anjum FM, SameenA, Gill WT. Meat as a functional food with special reference to probiotic sausages. Food Research International. 2011; 44: 3125-3133.
71. Tyopponen S, Petaja E, Mattila-Sandholm T. Bioprotectives and probiotics for dry sausages. International Journal of Food Microbiology. 2003;83: 233-244.
72. Jimenez-Colmenero, F,Delgado-Pando G. Fibre-enrichedmeat products. In: Delcour JA, Poutanen, K, editors. Fibre-rich and wholegrain foods.Oxford: Woodhead Publishing Limited; 2013, p. 329–347.
73. Verma AK, Banerjee R. Dietary fibre as functional ingredient in meat products: a novel approach for healthy living, a review. Journal of Food Science and Technology. 2010;47: 247-257.
74. Garcia-Iniguez C, Larequi E, Rehecho S, Calvo MI, Cavero RY, Navarro-Blasco I, Astiasaran I, Ansorena D. Selenium, iodine, ω-3 PUFA and natural antioxidant form Melissa officialis L: A combination of components for healthier dry fermented sausage formulation. Meat Science. 2010; 85: 274–279.
75. Caceres E, Garcia ML, Selgas MD. Design of a new cooked meat sausage enriched with calcium. Meat Science. 2006;73: 368-77.
76. Navas-Carretero S, Cuervo M, Abete I, Zulet MA, Martinez JA. Frequent consumption of selenium-enriched chicken meat by adults causes weight loss and maintains their antioxidant status. Biological Trace Element Research. 2011;143: 8-19.
77. Cofrades S, Sandoval LS, Delgado-Pando G, Lopez-Lopez I, Ruiz-Capillas C, Jimenez-Colmenero F. Antioxidant activity of hydroxytyrosol in frankfurters enriched with n-3 polyunsaturated fatty acids. Food Chemistry. 2011a;129: 429-436.
78. Fernandez-Lopez J, Fernandez-Gines JM, Aleson-Carbonell L,Sendra E,Sayas-Barbera E, Perez-Alvarez JA. Application of functional citrus by-products to meat products. Trends in Food Science & Technology. 2004; 15: 176-185.
79. Sanchez-Escalante A, Djenane D,Torrescano G, Beltran JA, Roncales P. The effects of ascorbic acid, taurine, carnosine and rosemary powder on colour and lipid stability of beef patties packaged in modified atmosphere. Meat Science. 2001;58: 421-429.
80. Caceres E, Selgas MD, Garcia ML. Research & Development: Conventional and fat-reduced cooked meat sausages enriched with folic acid. Fleischwirtschaft International: Journal for Meat Production and Meat Processing. 2008; 58-60.
81. Calvo MM, Garcia ML, Selgas MD. Dry fermented sausages enriched with lycopene from tomato peel. Meat Science. 2008;80: 167-172.
82. Sanchez-Escalante A, Torrescano G, Djenane D, Beltran JA, Roncales P. Combined effect of modified atmosphere packaging and addition of lycopene rich tomato pulp, oregano and ascorbic acid and their mixtures on the stability of beef patties. Food Science and Technology International. 2003;9: 77-84.
83. Csapo I, Incze K, Kovacs A, Zelenak L, Zsigo J. 2006. Development of meat products with lutein for eye health. In: Troy D, Pearce R, Byrne B, Kerry J, editors. 52nd International Congress of Meat Science and Technology.The Netherlands: Wageningen Academic Publishers; 2006, p. 687-688.
84. Daly T, Ryan E, Aherne SA, O’Grady MN, Hayes J, Allen P, O’Brien NM. Bioactivity of ellagic acid-, lutein-or sesamol-enriched meat patties assessed using an in vitro digestion and Caco-2 cell model system. Food Research International. 2010; 43: 753-760.
85. Granado-Lorencio F, Lopez-Lopez I, Herrero-Barbudo C, Blanco-Navarro I, Cofrades S, Perez-Sacristan B, Jimenez-Colmenero F. Lutein-enriched frankfurter-type products: Physicochemical characteristics and lutein in vitro bioaccessibility. Food Chemistry. 2010;120: 741-748.
86. Saleh NT, Ahmed ZS. Impact of natural sources rich in provitamin A on cooking characteristics, color, texture and sensory attributes of beef patties. Meat Science. 1998; 50: 285-293.
87. Pizzocaro F, Senesi E, Veronese P, Gasparoli A. Mechanically deboned poultry meat hamburgers. 2: Protective and antioxidant effect of the carrot and spinach tissues during frozen storage [chicken-turkey-Veneto]. IndustrieAlimentari (Italy). 1998
88. Ganhao R, Morcuende D, Estevez M. Protein oxidation in emulsified cooked burger patties with added fruit extracts: Influence on colour and texture deterioration during chill storage. Meat Science. 2010;85: 402-409.
89. Nissen LR, Byrne DV, Bertelsen G, Skibsted LH. The antioxidative activity of plant extracts in cooked pork patties as evaluated by descriptive sensory profiling and chemical analysis. Meat Science. 2004;68: 485-495.
90. Haak L, Raes K, De Smet S. Effect of plant phenolics, tocopherol and ascorbic acid on oxidative stability of pork patties. Journal of the Science of Food and Agriculture. 2009;89: 1360-1365.
91. Cofrades S, I. Lopezâ€Lopez I, Jimenezâ€Colmenero F. Applications of Seaweed in Meatâ€Based Functional Foods. Handbook of marine macroalgae: Biotechnology and Applied Phycology; 2011b, p. 491-499.
92. Desmond E. Reducing salt: A challenge for the meat industry. Meat Science. 2006;74: 188-196.
93. Ruusunen M, Puolanne E. Reducing sodium intake from meat products. Meat Science. 2005; 70: 531-541.
94. Jin H, Xu CX, Lim HT, Park SJ, Shin JY, Chung YS, Lee YS. High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signaling. American Journal of Respiratory and Critical Care Medicine. 2009; 179: 59-68.
95. Shahidi F, Synowiecki J. Protein hydrolyzates from seal meat as phosphate alternatives in food processing applications. Food Chemistry. 1997;60: 29-32.
96. Demeyer D, Honikel K, De Smet S. The World Cancer Research Fund report 2007: A challenge for the meat processing industry. Meat Science. 2008; 80: 953-959.
97. Corpet DE. Red meat and colon cancer: should we become vegetarians, or can we make meat safer? Meat Science. 2011;89: 310-316.
98. Ferguson LR. 2010. Meat and cancer. Meat Science. 2010; 84: 308-313.
99. Garci-Martin A, Fonseca CS, Bastida S, Vazquez-Velasco M, Gonzalez-Torres L, Benedi J, Sanchez-Muniz FJ. Restructured meat containing Himanthalia elongata acts as a competitive α glucosidase inhibitor. Potential utilities. 11 Encontro de Química dos alimentos. Bragança (Portugal): Qualidade dos alimentos: Novosdesafios. 2012.
100. Gonzalez-Torres L, Churruca I, Schultz Moreira AR, Bastida S, Benedi J, Portillo MP, Sanchez-Muniz FJ. Effects of restructured pork containing Himanthaliaelongata on adipose tissue lipogenic and lipolytic enzyme expression of normo-and hypercholesterolemic rats. Journal of Nutrigenetics and Nutrigenomics. 2012; 5: 158-167.
101. Olivero-David R, Schultz-Moreira A, Vazquez-Velasco M, Gonzalez-Torres L, Bastida S, Benedí J, Sanchez-Muniz FJ. Effects of Nori-and Wakame-enriched meats with or without supplementary cholesterol on arylesterase activity, lipaemia and lipoproteinaemia in growing Wistar rats. British Journal of Nutrition. 2011;106: 1476-1486.
102. Vossen E, Raes K, Maertens L, Vandenberge V, Haak L, Chiers K, De Smet S. 2012. Diets containing nâ€3 fatty acidsâ€enriched pork: Effect on blood lipids, oxidative status and atherosclerosis in rabbits. Journal of Food Biochemistry. 2012;36: 359-368.
103. Aggett PJ, Antoine JM, Asp NG, Bellisle F, Contor L, Cummings JH, Rechkemmer G. 2005. Process for the assessment of scientific support for claims on foods. European Journal of Nutrition. 2005;44: 1-31.
104. Aggett P, Antoine JM, De Vries J, Gallagher A, Hendriks H, Kozianowski G, Meijer G, Richarson D, Rondeau V, Tweedie G, Welch R, Wittwer J. Beyond Passclaim, Guidance to substantiate health claims on foods. In: Yates K,editor. ILSI Europe Report Series; 2010, p. 7–19. (ISBN: 9789078637219).
105. Pan A, Sun Q, Bernstein AM, Schulze MB, Manson JE, Stampfer MJ, Hu FB. Red meat consumption and mortality: results from 2 prospective cohort studies. Archives of Internal Medicine. 2012; 172: 555-563.
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