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Volume: 2, Issue: 5, Sep-Oct, 2014

Sep-Oct, 2014

DOI: 10.7324/JABB.2014.2503

Research Article

Anti-candidal activities of some Myrtus communis L. extracts obtained using accelerated solvent extraction (ASE)

Elif Ayse Erdogan1, Gulden Goksen2, Ayse Everest1

  Author Affiliations


Abstract

Candida albicans is a very important organism in production of acute and chronic infections. It can be reason of serious infections in human immune compromised patients as nosocominal infections. In this study, We researched new anti-candida agents from Myrtus communis extracts by ASE (Accelerated Solvent Extraction). We were also determined Gallic, Ferulic, Quercetin phenolic compounds known charged with antimicrobial activity by HPLC (High-performance Liquid Chromatography). Gallic acid (2,424 mg/g) and Quercetin (2,289 mg/g) were detected in high amounts in Acetone extract and Methanol extract while Ferulic (0,018 mg/g; 0,038 mg/g; 0,006mg/g) was recorded in low amounts in Methanol, Ethanol and Ethly acetate extracts, respectively. Methanol, Acetone, Ethanol and Ethly acetate extracts showed good anti-candida activity against C. albicans, with Minimum Inhibitory Concentration (MIC) ranging from 0.187 to 1,5 mg/mL; Minimum Fungicidal Concentration (MFC) ranging from 0,375 to 3 mg/mL.

Keywords:

Candida albicans, Myrtus communis, ASE (Accelerated Solvent Extraction), Anti-candidal.



Citation: Elif Ayse Erdogan, Gulden Goksen and Ayse Everest. Anti-candidal Activities Of Some Myrtus Communis L. Extracts Obtained Using Accelerated Solvent Extraction (ASE). J App Biol Biotech. 2014; 2 (05): 012-014. DOI: 10.7324/JABB.2014.2503


Copyright: Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

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