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Volume: 6, Issue: 5, Sep-Oct, 2018
DOI: 10.7324/JABB.2018.60509

Opinion

Long Non-Coding RNAs and their “Orchestration” in Cancers

Venkata Narasimha Kadali1, Sheji Chandran1, Smitha Murthy2

  Author Affiliations


Abstract

The behavior of “mysterious” long non-coding RNAs (LncRNAs) in cells and in cancers is quite fascinating. Their diverse and complex functions have astonished the entire scientific community. LncRNAs are absolutely diversified in nature and can execute a decisive task to regulate the genes in conjunction with developmental processes. They emerged as “key orchestrators” in cancers because of their involvement in cell proliferation, migration, and invasion. In this precise opinion, we first discuss the role of lncRNAs in various processes in the cell, and later, we brief the participation of lncRNAs in cancers with a note on their protein-coding potential.

Keywords:

Long non-coding RNA, LncRNAs in cancer, Protein-coding potential of lncRNA.



Citation: Kadali VN, Chandran S, Murthy S. Long non-coding RNAs and their “orchestration” in cancers. J App Biol Biotech. 2018;6(05):57-60.
DOI: 10.7324/JABB.2018.60509


Copyright: Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

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